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The statement that in cities, 2 out of 5 people killed in motor vehicle accidents are pedestrians highlights a critical issue regarding road safety in urban areas. This statistic indicates a significant risk that pedestrians face, especially in densely populated environments where vehicle traffic is higher. Understanding these statistics is essential for raising awareness about pedestrian safety and the need for protective measures such as crosswalks, traffic signals, and reduced speed limits in areas with heavy foot traffic.

While pedestrian deaths do affect various demographics, it's important to note that not all fatal incidents involve teenagers as the primary group affected. Factors such as age, location, and the nature of the accident all contribute to the context of pedestrian safety. In this instance, recognizing the correct statement emphasizes the role of urban design and traffic regulation in protecting vulnerable road users like pedestrians.